NAREB: a EU-funded research project for combating antibiotic resistance
18th November 2015: European Antibiotic Awareness Day 
The World Health Organization has declared antibiotic resistance as one of the three greatest threats to human health . This has promoted extensive efforts world wide in order to, for example, implement strategies for a rational use of already existing antibiotics, aimed at stopping and reversing the increasing incidence of infections caused by drug resistant microorganisms, such as methicillin resistant Staphylococcus aureus (MRSA) and multidrug resistant Mycobacterium tuberculosis (MDT-TB).
In the European Union, the ECDC has alerted on the increase of antibiotic resistance rates , especially on certain pathogens such as MRSA (which have incident rates above 25% in some European countries) and MDR-TB . Infections caused by MRSA or MDR-TB are often difficult to treat, usually require intensive care treatment with a long hospitalization, have increased morbidity and mortality rates, and overall, have a great economic impact in both developed and developing countries. Then, novel therapeutic strategies are urgently needed. It is widely accepted that the problem of antimicrobial resistance needs for international cooperation, as well as concerted efforts at the national level.